Aggressive Giant Cell Tumor of Bone in Elderly Female: an Unusual Age and Misdiagnosed on MRI as a Metastasis

侵襲性骨巨細胞瘤一個年長女性個案報告：少見發生年紀及核磁共振影像學誤診斷為腫瘤轉移

林炫佑(Husan-Yu Lin) ； 謝國顯(Kuo-Hsien Hsieh) ； 張祐剛(Yu-Kang Chang) ； 陳玉珍(Yu-Chen Chen)

《童綜合醫學雜誌》 13卷2期 (2019/12) Pp. 92-95

https://doi.org/10.3966/207135922019121302005

摘要

Background and purpose: Giant cell tumor (GCT) of bone, a locally aggressive albeit benign neoplasm, accounts for 3%-8% of all primary bone tumors. Approximately 60%-70% of patients with GCTs of bone are 20-40 years of age, whereas GCTs are very rare in those above the age of 55 years. Although many case studies on GCTs have been published, extensive search of the literature reveals few reports of elderly patients with GCTs. One case series of ten elderly patients with GCT of bone has reported that there were no differences in the characteristics of GCTs including tumor location, radiographic features, and clinical course present the case of a 74-year-old female with aggressive GCT of the left femoral condyle with an extended lesion, which was misdiagnosed by imaging studies.

關鍵字

diagnosis ； elderly ； magnetic resonance imaging

並列摘要

研究背景與目的：骨巨細胞瘤的盛行率大約占所有骨腫瘤的3-8%，是一種良性局部侵襲性腫瘤，大約60-70%的病患年齡在20-40歲之間，病患年齡超過55歲以上者非常罕見，雖然目前已有許多骨巨細胞瘤的病例報告及相關研究，但是少文獻是在探討高齡病患的部分。方法：我們找到有一篇關於骨巨細胞瘤在老年人的病例系列，來跟我們的個案來比較。結果及討論：在年紀大及年輕的個案，骨巨細胞瘤在位置、影像檢查或臨床表現上並沒有很大差異，而我們提出一個個案的報告，是關於一個年長女性，在遠端股骨有個膨大的病灶（侵襲性的骨巨細胞瘤），影像學上被誤診的個案。

並列關鍵字

骨巨細胞瘤 ； 老年人 ； 核磁共振診斷