Unilateral Vocal Cord FDG Uptake Caused by Contralateral Vocal Cord Paralysis

Translated Titles





李岳(Yueh Lee);邱創新(Chuang-Hsin Chiu);鄭澄意(Cheng-Yi Cheng);林立凡(Li-Fan Lin)

Key Words

fluorine-18 fluorodeoxyglucose (FDG) ; positron emission tomography/computed tomography (PET/CT) ; recurrent laryngeal nerve ; vocal cord paralysis ; 聲帶麻痺 ; 喉返神經 ; 氟-18氟化葡萄糖 ; 正子造影



Volume or Term/Year and Month of Publication

34卷2期(2021 / 06 / 01)

Page #

96 - 100

Content Language


Chinese Abstract

A 70-year-old smoking male presented with cough and hoarseness was diagnosed with adenocarcinoma of the left upper lobe of the lung. Fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) was performed for staging. In addition to FDG-avid primary lung tumor and left hilar lymph node, a focus of intense FDG uptake was incidentally noted at the posterior aspect of the left vocal cord. Laryngoscopy was done to exclude synchronous laryngeal malignancy. Normal appearance of the left vocal cord with contralateral vocal cord paralysis was found. Follow-up FDG PET/CT performed 2.5 years later revealed no discernible abnormal FDG uptake at the vocal cords, supported that the previously noted focal FDG uptake at the left vocal cord might be a benign etiology (e.g., compensatory overuse of the non-paralyzed vocal cord). One of the major causes of asymmetrical vocal cord FDG uptake is compensatory overuse of the unaffected vocal cord caused by unilateral vocal cord paralysis, which is not uncommon in patients with primary lung cancer and mediastinal surgery. We recommended nuclear physicians to be aware of this pitfall to avert a false-positive PET interpretation. Furthermore, diazepam administration or minimized vocalization before PET scan might be helpful to avoid this pitfall.

English Abstract


Topic Category 醫藥衛生 > 基礎醫學
醫藥衛生 > 內科
工程學 > 核子工程