Physics is a science based on observation and experiment. Introducing Multisim into the teaching of physics and electricity in senior high school can not only overcome the shortcomings of traditional teaching, but also improve the quality of teaching. In this way, students can understand and master the theoretical knowledge, stimulate their interest in learning, and cultivate their practical ability and innovation awareness. At the same time, it will add vitality to the new teaching methods of physics class and experiment under the new curriculum reform.