2010年臺灣馬匹馬流行性感冒之血清盛行率調查

Seroprevalence of Equine Influenza in Horses in Taiwan in 2010

周宏致(Hung-Chih Chou)

指導教授 ： 吳應寧

國立臺灣大學/獸醫專業學院/臨床動物醫學研究所/碩士(2012年)

https://doi.org/10.6342/NTU.2012.00438

摘要

馬流行性感冒（Equine Influenza, EI）為高接觸之傳染性疾病。馬流感病毒為正黏液病毒科（Orthomyxoviridae）之A型流行感冒病毒（Influenzavirus A），可感染所有年齡層之馬匹，其中以年輕馬較易感染。然而近十年內臺灣地區並無馬流行性感冒之流行病學調查。為了解臺灣馬匹馬流行性感冒之現況，於2010年5月至10月分別於臺灣北部(台北、桃園)、中部(新竹、苗栗、台中)、南部(高雄、屏東)和東部(花蓮、台東)，採集全臺馬場217匹馬之頸靜脈血液樣本，對馬流行性感冒病毒抗體進行酵素連結免疫吸收分析（enzyme-linked immunosorbent assay, ELISA）血清學檢測。結果顯示217個樣本的陽性率約為47%(103/217)，其中大部分的陽性馬場集中於北部、中部和南部。希望藉此建立臺灣馬流行性感冒之流行病學最新資料，並依據結果進行防疫策略之規劃與防治技術之研究與改進。

關鍵字

流行病學 ； 馬流行性感冒 ； 馬

並列摘要

Equine influenza (EI) is an acute, highly contagious disease worldwide. The EI virus belongs to the influenza virus A class of the Orthomyxoviridae family. Horses of all ages are susceptible to EI, especially foals. However, no epidemiologic evaluations of EI in Taiwan have been conducted within the past 10 years. To describe the current epidemiology of EI among horses in Taiwan, 217 samples of equine serum were collected from horses from 23 horse fields in 4 different regions of Taiwan between May and October 2010, i.e., the northern region (Taipei and Taoyuan), the central region (Hsinchu, Miaoli, and Taichung), the southern region (Kaohsiung and Pingtung), and the eastern region (Hualien and Taitung). Samples were tested by enzyme-linked immunosorbent assay (ELISA). Overall, approximately 47% (103/217) of samples were seropositive for EI. In addition, the high prevalence of EI was seen in horse fields concentrated in northern, central, and southern regions of Taiwan. We used statistical methods to analyze the seroprevalance of EI in Taiwan and assess our ELISA results. Future research should focus on delineating the epidemiology of EI. Furthermore, measures to prevent EI outbreaks should be designed and promptly implemented.

並列關鍵字

Epidemiology ； Equine Influenza ； Horse

參考文獻

[1] 林嘉勇。臺灣馬匹日本腦炎流行病學調查。國立臺灣大學臨床動物醫學研究所碩士論文，台北，17-18，2011。

[7] Chan KY, Wang CH, Wu YL. Serological survey of equine Piroplasmosis, equine granulocytic Anaplasmosis, and equine Lyme disease in Taiwan. Taiwan Vet J 36: 261-267, 2010.

[5] Buonagurio DA, Nakada S, Parvin JD, Krystal M, Palese P, Fitch WM. Evolution of human influenza A viruses over 50 years: rapid, uniform rate of change in NS gene. Science 232: 980-982, 1986.

[6] Britton AP, Robinson JH. Isolation of influenza A virus from a 7-day-old foal with bronchointerstitial pneumonia. Can Vet J 43: 55, 2002.

[8] Chapman PS, Green C, Main JPM, Taylor PM, Cunningham FM, Cook AJC, Marr CM. Retrospective study of the relationships between age, inflammation and the isolation of bacteria from the lower respiratory tract of thoroughbred horses. Veterinary Record 146: 91-95, 2000.