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  • 學位論文

利用決策樹分析子宮內膜異位病患施行超音波導引穿刺術乙醇硬化治療

To Analysis the Relapse of Endometriosis’s Patient Treated with Ultrasound Guided Aspiration of Ovarian Endometrioma and Ethanol Sclerotherapy by Using Decision Tree

指導教授 : 黃連進

摘要


自1991年以來,超音波導引子宮內膜穿刺手術已被當成避免外科手術的替代治療方案。藉由囊腫穿刺能減小腫瘤體積,破壞囊腫壁,減輕沾黏情形與提升復原機會;但如祇執行單純囊腫穿刺手術而未施行其他附加治療的易引發高復發率(28.5%至100%)。所以為了降低因穿刺手術造成的高復發率,一些醫療團體已採用結合超音波導引子宮內膜穿刺手術合併四環素、甲氨蝶呤,或白細胞介素-2灌流的治療方式,其復發率依次分別為46.9%、18.1%與40%。臨床療效的參考標準,多以對單一子宮內膜囊腫施行乙醇灌流達10分鐘的復發率(14.9%)作為評斷的基準點。 本研究與國內某醫學中心所屬生殖醫學中心合作,針對曾接受過子宮內膜異位相關手術後復發之病患資料做研究,本研究依據診斷定義、臨床症狀與治療措施,規劃匯入臨床病例資料利用資料探勘的技術與分析,以囊腫數量作為決策樹分析預測的項目,發掘出有用的特徵以及彼此相互間的關聯性,試圖將來源資料中隱藏的資訊挖掘出來,運用決策樹將資料依據不同的變數循序產生分析結果,分析資料之特質與異同點,期望能找出與檢驗數據與臨床症狀相關重要決策因子,提供臨床專科醫師診斷與治療的參考。

並列摘要


Ultrasound guided aspiration of ovarian endometrioma had been tried as an alternative therapeutic modality in patients who undesired for surgery or surgical approach is contraindicated since 1991. But simple aspiration leaves the capsule without treatment that results in high recurrence rate (28.5% to 100%). In order to reduce recurrence after aspiration, some groups have combined ultrasound-guided aspiration with instillation of tetracycline, methotrexate, recombinant interleukin-2, with the recurrence rates of 46.9%, 18.1%, and 40% respectively. Noma et al. reported that conduct of ethanol instillation for more than 10 minutes particularly for a case with a single endometrial cyst is considered most effective from the standpoint of recurrence (14.9%). This research works together with Reproduction Medicine Center of Medicine Center in Taiwan Area. Our goal is to analyse patients with recurrent pelvic cyst who underwent surgical intervention. The research data basis clinical diagnosis, symptoms and medical intervention classification, and define the cyst numbers as forecast project target. We try to use decision tree, methodology of data mining technology, to find the useful characteristic as well as each other mutually connection. The expectation can discover with examines the data and the clinical symptom correlation important decision-making factor, provides clinical faculty doctor to diagnose and the treatment reference.

參考文獻


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被引用紀錄


張瓊姿(2008)。關聯式法則在子宮內膜異位臨床病徵的應用〔碩士論文,淡江大學〕。華藝線上圖書館。https://doi.org/10.6846/TKU.2008.00492

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