Title

接受放射線治療癌症患者之中醫體質研究

Translated Titles

The Study of the Cancer Patients’ Constitution Changes Before and After Receiving Radiotherapy

DOI

10.6830/CMU.2011.00083

Authors

張慈文

Key Words

體質 ; 放射線治療 ; constitution ; radiotherapy

PublicationName

中國醫藥大學中醫學系碩士班學位論文

Volume or Term/Year and Month of Publication

2011年

Academic Degree Category

碩士

Advisor

蘇奕彰

Content Language

繁體中文

Chinese Abstract

癌症的發生率及死亡率居高不下,現代醫學使用放射療法作為其中一種主要的治療方式。然而,放射療法在治療過程中,難免對於正常細胞帶來損傷,產生副作用。現代醫學的評估,副作用的產生與放療的照射方式、劑量、及病人體質有很大的關係,而體質一直是現代醫學難以突破的課題,所以,本研究嘗試從中醫理論的角度評估患者體質與副作用的相關性。 本研究自97年3月1日起至98年4月11日止,於三軍總醫院放射腫瘤科門診進行取樣施測,完成第一、二階段評估的總共有46位病患。中醫體質的評估,採用BCQ中醫體質量表;放射線療法副作用的評估,採用美國放療組織(RTOG)所研發出的分級量表,並進行T檢定、淨相關檢定等統計分析。 本研究之結果顯示:病患接受放射線治療後的各類型體質(陰血虛、陽氣虛、痰濕瘀滯)分數皆有顯著上升(加重);副作用嚴重度與總照射劑量無顯著相關,反而與治療前的痰瘀體質和治療過程中陰血虛的變化量呈顯著正相關。這意謂著:體質會受放射線療法影響而轉變,更與副作用之嚴重度息息相關,藉由體質分析,可提供分期治療之策略,彰顯中醫體質調整之重要性。

English Abstract

The morbidity and mortality rate of cancer are still high. Radiotherapy is the major method for cancer treatment in modern medicine. However, the cell damage caused by radiotherapy will result in certain degree of adverse effects. The manifestations of the adverse effects are in relation with the radiation methods, dosage and the constitution of the patients. Thus, this study aimed to explore the constitution changes of the cancer patients before and after receiving radiotherapy. This study was conducted from March 01, 2008 to November 11, 2009. Forty-six patients with different cancer diagnosis were observed in the outpatient department of Radiation Oncology in Tri-service General Hospital. The patients’ constitution was evaluated by body constitution questionnaire (BCQ) and their adverse effects were assessed by grading table made by RTOG. The result revealed the scores of Yin-Xu, Yang-Xu and Stasis constitution all elevated after radiotherapy. There was no significant correlation between the severity of adverse effects and total dose of radiation; but the severity of adverse effects was significantly correlated with the score of Stasis constitution and the change of Yin-Xu constitution score. Our results implies that the patient’ constitution will change after radiotherapy and has correlation with the severity of adverse effects. Therefore, the patients’ adverse effects may be prevented by adjusting their constitution.

Topic Category 醫藥衛生 > 中醫藥學
中醫學院 > 中醫學系碩士班
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