並列摘要
Bronchopulmonary dysplasia (BPD) is a major complication of premature infants. The prevalence is not decreased this decade in spite of. advanced neonatal care. The pathophysiology of BPD is multifactorial. Prevention of BPD by avoiding prematurity, gentle ventilation care and prevention of pulmonary inflammation is the cornerstone of management. Once BPD developed, it is remarkable resistant to pharmacological treatment, since most agents only target one of the possible mechanisms such as bronchoconstriction, airway hyperactivity, pulmonary edema, airway inflammation and chronic lung injury and repair. This paper will review the usage of these agents in the prevention and treatment of BPD.
延伸閱讀
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