Patient-triggered Ventilation of Newborns

The use of time-cycled, pressure-limited, intermittent mandatory ventilation (IMV) in newborns often leads to asynchrony between the ventilator and the infant's own spontaneous breathing. Asynchrony has been associated with several adverse physiological effects. Advances in microprocessor technology have enabled ventilators to achieve synchronization between mechanical breaths and the infant's spontaneous breathing, this is known as ”Patient-triggered ventilation (PTV)”. Evidence indicates that PTV is associated with several short-term benefits. Meta-analyses also have demonstrated that PTV facilitates weaning, and that the duration of ventilation is shorter than that of conventional IMV. Although evidence is lacking for long-term benefits such as reduction in mortality rate and incidence of intraventricular hemorrhage and chronic lung disease, PTV has become a standard approach in most neonatal units throughout the world. The clinician should have a better understanding of its modalities, controls, monitoring, benefits, and limitations in newborns. Further randomized trials are needed to assess the long-term benefits of PTV in the modern era.

並列關鍵字

Patient-triggered ventilation ； Synchronization ； Mechanical ventilation ； Newborn ； Preterm infants

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