- 期刊
Pulmonary and Gastric Mucosa-associated Lymphoid Tissue Lymphoma in a Patient with Sjögren's Syndrome: A Case Report
一位罹患修格蘭氏症候女性合併有肺及胃粘膜相關淋巴組織淋巴瘤：病例報告
摘要
粘膜相關淋巴組織淋巴瘤可能會因為特定的自體免疫疾病（修格蘭氏症候、全身性紅斑性狼瘡、橋本氏甲狀腺炎）或感染（幽門螺旋桿菌）而引起。粘膜相關淋巴組織淋巴瘤是相當良性的腫瘤，常侷限在某一器官很久的時間，很少有同時發生兩處以上的情形，我們報告一位長時間有眼乾及口乾症狀的56歲女性因咳血住院，以電腦斷層導引穿刺術評估肺部病灶，因檢體太小無法作確定診斷，住院中意外發現胃粘膜相關淋巴組織淋巴瘤，進而以聚合酵素鏈鎖反應方法診斷肺部病灶亦為粘膜相關淋巴組織淋巴瘤。在肺部診斷此疾病需要較大的檢體，電腦斷層導引穿刺術的診斷率並不高，但我們可以根據臨床上相關的疾病及影像學的特徵，懷疑此疾病並輔以聚合酵素鏈鎖反應方法，減少需要手術的風險並提高診斷率。
並列摘要
Mucosa-associated lymphoid tissue (MALT) lymphoma may arise from certain autoimmune diseases (Sjögren's syndrome, systemic lupus erythematosus, Hashimoto's thyroiditis) or infections (Helicobacter pylori). MALT lymphoma is indolent and often localized for a long time. Coexistence of MALT lymphomas in 2 or more sites is rare. We reported a patient with long-term symptoms of dry eyes and dry mouth who was admitted for evaluation of lung lesions. The computed tomography (CT) guided biopsy specimen was too small to yield a definite diagnosis. The diagnosis of pulmonary MALT lymphoma is based on the pathological examination, often needing a larger specimen obtained through surgery. This patient was diagnosed with Sjögren's syndrome and unexpected gastric MALT lymphoma during this hospitalization. The diagnosis of pulmonary MALT lymphoma was made using the polymerase chain reaction (PCR) technique.