生物醫學文獻知識視覺化呈現

張永達

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College of Engineering > Graduate Institute of Biomedical Engineering

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生物醫學文獻知識視覺化呈現

Knowledge Visualization in Biomedical Literatures

張永達 , Masters　　Advisor：翁昭旼　　

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基因本體論；文件探勘；知識視覺化呈現； Gene Ontology ； document retrieval ； knowledge visualization

Abstract │ Reference (57) │ Altmetrics

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Under the influence of developed information technology in these years, biomedical circles have numerous e-documents published in various periodicals everyday; however, it is very importance but difficult to find out specific and meaningful information to researchers from numerous and complicated biomedical literatures. Therefore, if the processing time of these literatures by the researchers could be reduced, it is to save manpower, material and time indirectly; thus how to extract relevant knowledge from documents will certainly become the key of the problem.

But what document shall begin with? How to process data effectively? How to present after process? For the process of biomedical literatures and extract of knowledge, the traditional document mining technology is no longer sufficient. Therefore, this research will introduce the concept of "Gene Ontology" to extract, process, and present the knowledge of describing gene function in biomedical literatures. This research is divided to several stages: first is to process the original information of Gene Ontology, and then is to extract and present relevant information from biomedical literatures, and design a graphic user interface system – OntoMarker to enable researchers to extract the important information that existed in single literature or certain topic through easy operation. Finally is to verify the system by the medical literatures relevant to CARD15/NOD2 gene in PubMed/MEDLINE. The verified results are true and feasible, and helpful to researchers.

Reference ( 57 ) 〈TOP〉

REF 1-1: Human Genome Project 人類基因計劃 http://www.genome.gov/
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REF 1-2: Entrez PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
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REF 1-4: The Gene Ontology http://www.geneontology.org/
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REF 2-3: Gruber, T. "Ontolingua:A translation approach to portable ontology specifications". Knowledge Acquisition 5(2), 1993, pp. 199-200.
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REF 2-5: Mouse Genome Informatics http://www.informatics.jax.org/
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