整合超音波功能性影像判定組織燒灼面積變化與變性程度：可行性研究

黃重琨

doi:10.6342/NTU.2010.01570

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整合超音波功能性影像判定組織燒灼面積變化與變性程度：可行性研究

Combination of Functional Ultrasonic Images to Evaluate the Tissue Ablation and Denaturation: a Feasibility Study

黃重琨 , Masters　　Advisor：朱錦洲　　Co-advisor ：張建成

繁體中文 DOI： 10.6342/NTU.2010.01570

超音波； B-mode影像； Nakagami影像；彈性影像； ultrasound ； B-mode image ； Nakagami image ； elasticity image

Abstract │ Reference (37) │ Altmetrics

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The ultrasound diagnostic imaging has become one of the most used tool in medical examination, since it has the advantages of non-invasive, harmless, low price, real-time and high mobility properties. However, because of ultrasound B-mode image need to be construed by instructed doctor  and can not be used to quantitative analysis, many statistical models were proposed in order to provide more objective diagnostic. Besides, some functional ultrasound images were also developed for pathological changes of tissue.
In this study, we utilized three different functional ultrasound images: B-mode image, Nakagami image and elasticity image. In the first part, we used phantom experiment to verify the Nakagami m parameter’s physical mean. We design four different phantom ,and verify Nakagami m parameter with Nakagami imaging and elasticity imaging.
The second part of study is tissue ablation experiment. In recent year, ablation technique has been a common treatment technology. However, it is not easy to find out the affected part with bare eyes during ablation therapy, therefore some imaging tools have been carried out. In this study, we ablated pork tissue by microwave ablation technique, then we used B-mode image, Nakagami image and elasticity image to observe the change of tissue and evaluate the area of tissue ablation in order to find out the suitable imaging tool to aid in ablation.

Reference ( 37 ) 〈TOP〉

[1] D. Christensen, Ultrasonic bioinstrumentation: John Wiley & Sons Inc, 1988.
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[2] K. Shung and G. Thieme, Ultrasonic scattering in biological tissues: CRC, 1993.
連結：
[3] P. Shankar, "A general statistical model for ultrasonic backscattering from tissues," ieee transactions on ultrasonics, ferroelectrics, and frequency control, vol. 47, pp. 727-736, 2000.
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[4] J. Ophir, I. Cespedes, H. Ponnekanti, Y. Yazdi, and X. Li, "Elastography: A quantitative method for imaging the elasticity of biological tissues," Ultrasonic Imaging, vol. 13, pp. 111-134, 1991.
連結：
[5] C. Burckhardt, "Speckle in Ultrasound B-Mode Scans," Sonics and Ultrasonics, IEEE Transactions on, vol. 25, pp. 1-6, 1978.
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