製備多孔性聚乳酸微粒於軟組織填補劑之開發

吳書璇

doi:10.6841/NTUT.2014.00754

34.239.176.198，Hello！

Close
Search Quick Search Advanced Search Publication Search	Personal Service Member Login Searching History Use Bonus Card SYMSKAN
Browse Browse by University of Graduate Thesis Browse by Pinyin of Graduate Thesis Browse by Conference Proceedings Topic Browse by Conference Proceedings Publisher Browse by Pinyin of Conference Proceedings Browse by eBook Category Browse by eBook Topic Browse by eBook Publisher
Customer Services Authorize Airiti Recommend a Journal

Search Symbol (Half-width)	Description of Search Symbols
Space	"AND" indicates the intertwining of key terms used in a search
Double Quotation Marks ("") ( " " )	Double quotation marks indicate the beginning and end of a phrase, and the search will only include terms that appear in the same order of those within the quotations. Example: "image process" ： " image process "
?	Indicates a variable letter. Entering two ? will indicate two variable letters, and so on. Example: "Appl?", search results will yield apple, apply… e , appl y … ( (often used to English word searches) )
*	Indicates an unlimited number of variable letters to follow, from 1~n. Example: Enter "appl*", search results will yield apple, apples, apply, applied, application…(often used in English word searches) e , appl es , appl y , appl ied , appl ication … ( (often used to English word searches) )
AND、OR、NOT	Boolean logic combinations of key words is a skill used to expand or refine search parameters. (1) AND (1) AND: Refines search parameters (2) OR (2) OR: Expands search parameters (3) NOT: Excludes irrelevant parameters

DOI stands for Digital Object Identifier （ D igital O bject I dentifier ） ,
and is the unique identifier for objects on the internet. It can be used to create persistent link and to cite articles.

Using DOI as a persistent link

To create a persistent link, add「http://dx.doi.org/」「 http://dx.doi.org/ 」 before a DOI.
For instance, if the DOI of an article is 10.5297/ser.1201.002 , you can link persistently to the article by entering the following link in your browser: http://dx.doi.org/ 10.5297/ser.1201.002 。
The DOI link will always direct you to the most updated article page no matter how the publisher changes the document's position, avoiding errors when engaging in important research.

Cite a document with DOI

When citing references, you should also cite the DOI if the article has one. If your citation guideline does not include DOIs, you may cite the DOI link.

DOIs allow accurate citations, improve academic contents connections, and allow users to gain better experience across different platforms. Currently, there are more than 70 million DOIs registered for academic contents. If you want to understand more about DOI, please visit airiti DOI Registration （ doi.airiti.com ）。

Data Source

College of Engineering > Graduate Institute of Biotechnology
Bio-Agriculture > Biological Science

Bibliography Management Tool

Related Links

Report an Issue

Purchase Single Articles

Download PDF

製備多孔性聚乳酸微粒於軟組織填補劑之開發

Preparation of porous polylactic acid particles for the development of soft tissue fillers

吳書璇 , Masters　　Advisor：方旭偉　　

繁體中文 DOI： 10.6841/NTUT.2014.00754

聚乳酸；雙乳化法；填補劑； Polylactic acid ； Double emulsion solvent evaporation method ； Filler

Abstract │ Reference (24) │ Altmetrics

Abstract 〈TOP〉

Parallel Abstract 〈TOP〉

The external force or disease made soft tissue defect, it not only lost normal function of the skin, but also affected the psychological trauma. Therefore we need good treatment to improve organizational defects of subcutaneous soft tissue repair problems. The stimulatory fillers induced autologous collagen production and had a long-term fill effects, Thus they became a good choice of clinically fill . However, there are still problems of the stimulatory fillers such as particle size, morphology irregular lead to granulation tissue swelling and other clinical problems need to be overcome. Therefore the purpose of the study was prepared porous polylactic acid particles to improve the uneven filling. The study was prepared many kinds of porous polylactic acid particles in a variety of double emulsion parameters and used the biocompatible porous polylactic acid particles, gene expression, and to optimize the dispersion well filler.
We used speed regulation and different volume ratio of polylactic acid and polyvinyl alcohol to make different sizes particles and increased the yield. In cell experiments, small polylactic acid particles had good activity and porous polylactic acid particles can reduce the degradation of collagen gene MMP1 expression.

Reference ( 24 ) 〈TOP〉

1. S. F. Dastoor, C. E. Misch and H. L. Wang, "Dermal Fillers for Facial Soft Tissue Augmentation," Journal of Oral Implantology, vol. 33, 2007, pp. 191-204.
連結：
3. E. G. Canty and K. E. Kadler, "Procollagen trafficking, processing and fibrillogenesis," Journal of Cell Science, vol. 118, 2005, pp. 1341-53.
連結：
5. S. Werner, T. Krieg and H. Smola, "Keratinocyte-fibroblast interactions in wound healing," Journal of Investigative Dermatology, vol. 127, 2007, pp. 998-1008.
連結：
6. J. H. Shim, D. W. Shin, T. R. Lee, H. H. Kang, S. H. Jin and M. Noh, "The retinoic acid-induced up-regulation of insulin-like growth factor 1 and 2 is associated with prolidase-dependent collagen synthesis in UVA-irradiated human dermal equivalents," Journal of Dermatological Science, vol. 66, 2012, pp. 51-59.
連結：
7. S. Kusin and J. Lippitz, "Skin Fillers," Disease-a-Month, vol. 55, 2009, pp. 236-256.
連結：

Altmetrics

〈TOP〉

E-mail ：

When an article is available to download, a notice will be sent to your mailbox address.

E-mail ：