Clinical Manifestations and Outcomes of Constrictive Pericarditis in Children

兒童時期窄縮性心包膜炎的臨床表現與預後

陳俊安(Chun-An Chen) ； 林銘泰(Ming-Tai Lin) ； 吳恩婷(En-Ting Wu) ； 呂立(Leigh Lu) ； 王主科(Jou-Kou Wang) ； 黃立民(Li-Min Huang) ； 陳益祥(Yih-Shang Chen) ； 張重義(Chung-I Chang) ； 邱英世(Ing-Sh Chiu) ； 吳美環(Mei-Hwan Wu)

《Journal of the Formosan Medical Association》 104卷6期 (2005/06) Pp. 402-407

https://doi.org/10.29828/JFMA.200506.0003

並列摘要

Background and Purpose: Constrictive pericarditis (CP) is rare in children. The purpose of this study was to define the clinical manifestations and outcomes of this disease
Methods: From January 1985 through December 2003, 8 patients with surgically confirmed CP were enrolled. Data on clinical characteristics, disease manifestations treatment, and outcomes were collected and analyzed.
Results: One patient had l-transposition of the great arteries (l-TGA) the other 7 patients had no underlying cardiovascular diseases None of the patients had direct evidence of tuberculous infection Age at disease onset ranged from 8 months to 13 years (median 10 years) and the interval between symptom onset and correct diagnosis ranged from 2 to 31 months (median 12 months) Major symptoms and signs included abdominal distension, hepatomegaly neck vein engorgement and ascites. Evidence of calcification on chest roentgenogram was found in 1 patient (12.5%). Computed tomography or magnetic resonance image studies showed pericardial thickening in 6 patients (75%) Seven patients underwent cardiac catheterization and all hemodynamic data met the diagnostic criteria for CP. All patients with structurally normal hearts survived during a median follow up of 31, months after pericardiectomy (range 5 to 103 months) The patient with l-TGA died of pneumonia 1 year after pericardiectomy Conclusions Symptoms and signs of right heart failure were common in children with CP The etiology of CP remains largely unknown. Patients with structurally normal hearts have good outcomes after pericardiectomy.

並列關鍵字

Constrictive pericarditis ； Disease attribute ； Pericardiectomy ； Retrospective studies