Dietary galactooligosaccharides improve skin health: a randomized double blind clinical trial

Objective: To study the effects of galactooligosaccharides (GOS) on the skin, we investigated skin-related parameters in healthy adults who received GOS for 12 weeks. Methods: This double-blind, randomized, placebo-controlled study included subjects divided into two groups (control and GOS) by stratified block randomization. The GOS group received 1 g of GOS twice a day, whereas the control group received only vehicle. Results: The results showed that the increase in corneometer values from baseline to week 12 was significantly greater in the GOS group than in the control group (6.91 vs. 2.88 arbitrary units, p＜0.05). The transepidermal water loss in the GOS group was reduced significantly after 12 weeks of GOS treatment (20.1 g/h/m^2 at baseline vs. 17.5 g/h/m^2 at week 12, p＜0.05). The differences in total and percentage of wrinkle areas between the two groups were statistically significant after 12 weeks of GOS treatment (p＜0.05). Conclusion: Our findings support that oral treatment with GOS is beneficial to the skin and present the possibility of new nutritional strategies for skin care.

並列關鍵字

galactooligosaccharide ； prebiotics ； probiotics ； skin hydration ； wrinkle

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