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25-Hydroxy-Vitamin D Demography and the Risk of Vitamin D Insufficiency in the South East Asian Nutrition Surveys (SEANUTS)

本文正式版本已出版,請見:10.6133/apjcn.092015.02

並列摘要


The South East Asian Nutrition Surveys (SEANUTS) were conducted from 2010 to 2011 in Indonesia, Malaysia, Thailand and Vietnam in country representative samples totalling16744 children aged 0.5 to 12 years. Information on socio-demographic and behavioural variables was collected using questionnaires and anthropometric variables were measured. In a subsample of 2016 children, serum 25-hydroxy-vitamin D (25(OH)D) was determined. Data were analysed using SPSS complex sample with weight factors to report population representative data. Children were categorized as deficient (<25 nmol/L), insufficient (<50 nmol/L), inadequate (<75 nmol/L) or desirable (≥75 nmol/L). In Malaysia and Thailand, urban children had lower 25(OH)D than rural children. In all countries, except Vietnam, boys had higher 25(OH)D levels and older children had lower 25(OH)D . Regional differences were seen in all countries and these remained even after correcting for age, sex and area of residence. In Thailand and Malaysia, 25(OH)D status was also associated with religion. The percentage of children with adequate 25(OH)D (≥75 nmol/L) ranged from as low as 5% (Indonesia) to 20% (Vietnam). Vitamin D insufficiency (<50 nmol/L) was noted in 40 to 50% of children in all countries. Logistic regression showed that girls, urban area, region within the country and religion significantly increased the odds for being vitamin D insufficient. The high prevalence of vitamin D insufficiency in the (sub) tropical SEANUTS countries suggests a need for tailored approach to combat successfully this problem. Promoting active and outdoor lives with safe sunlight exposure for skin synthesis of vitamin D along with food based strategies to improve its intake can be feasible options.

並列關鍵字

vitamin D status 25(OH)D children Malaysia Indonesia Thailand Vietnam aetiology

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