Oral Neurilemmomas-A Clinicopathological Study of 21 Cases

Oral neurilemmomas (ON) are rare oral lesions. Twenty-one cases of ONs diagnosed and treated in our institute during the period from January 1991 to June 2004 were analyzed in this study. There were 14 male and 7 female patients. The mean age of the 21 patients at the time of diagnosis was 30 (range, 14-67) years with a peak incidence of tumor occurrence in the third decade. The more-common sites for an ON were the tongue (8 cases) and buccal mucosa (5 cases). The clinical appearance of ONs was frequently a pink, movable mass. In only 1 case was palpation tenderness noted. The greatest dimension of the lesion was 2 cm with a mean of 1.0±0.5 cm. The duration of the lesion ranged from 10 days to 10 years with a median of 6 months. Of the 21 cases, the clinical diagnosis was a fibroma in 6, a mucocele in 4, a tongue or buccal tumor in 5, and others in 6. Surgical excision was the treatment of choice for all 21 lesions. None of the lesions showed recurrence after surgical excision. On the average, our 21 ONs contained 77%±16% Antoni A tissue and 23%±16% Antoni B tissue. We conclude that ONs occur most often in the third decade. The more-commonly affected sites are the tongue and buccal mucosa. ONs often present as a painless and movable mass which is very difficult to diagnose just based on their clinical features. Our ONs were mostly composed of Antoni A tissue, with much-smaller content of Antoni B tissue.

並列關鍵字

oral neurilemmoma ； schwannoma ； clinical feature ； histological feature

國際替代計量

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