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絨毛膜癌化學治療所致之全血球降低:一病例報告

Chemotherapy Induced Pancytopenia in Choriocarcinoma-A Case Report

摘要


EMA/CO乃治療高危險轉移性妊娠滋養層疾病中一種有效混合配方,但它所產生對生命有威脅之報告,則很少被報導。今我們報告一有高危險轉移性之絨毛膜癌患者,以EMA/CO來治療,不幸產生嚴重之病情,包括全血球降低、發燒、喉、外陰和手之潰瘍,以及上胃腸道出血。經過保守性治療後,一切痊癒。至今,自治療始已30個月,仍沒有任何復發現象。本文並討論這些併發症之預防之治療的方法。

並列摘要


EMA/CO is an active combination regimen for treatment of high risk metastatic gestational trophoblastic disease, but its life-threatening complications have hardly been reported. We present a case of high risk metastatic choriocarcinoma with a regimen incorporating EMA/CO. Unfortunately, a critical condition occurred to manifest pancytopenia, fever, ulcer of throat, vulvar and hand, as well as upper gastro-intestinal bleeding. The following conservative treatment attained a satisfactory outcome. To date 60 months after the initial treatment, there is no evidence of disease. Prevention and management of these complications would be discussed in this report.

並列關鍵字

choriocarcinoma chemotherapy pancytopenia

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