- 期刊
Castleman's Disease of the Pancreas: Report of a Case
胰臟的Castlemang氏疾病：病例報告
摘要
Castleman氏疾病是一種罕見的疾病，主要以身體一處或多處淋巴結增生來表現。Castleman氏疾病最好發於胸腔，發生在胰臟的情況甚為罕見。治療單一位置的Castleman氏疾病是手術切除，而對於多發性Castleman氏疾病的治療仍未有定論，一般是以化療為主。我們報告一例以手術成功治療的胰臟Castleman氏疾病。一名29歲女性主訴六個月來間歇性腹瀉，電腦斷層發現在胰臟腹部有一平滑、同質而界限分明之腫瘤。開腹手術時，將腫瘤順利的切除，組織病理檢驗顯示是Castleman氏疾病。病人術後復原平順，症狀逐漸改善，經一年追蹤並無復發。英文文獻上報告的胰臟Castleman氏疾病只有六例。雖然，胰臟Castleman氏疾病有一些無法手術切除，但大部份可完全切除。在此情況下，良好的預後是可預期的。
關鍵字
無資料並列摘要
Castleman's disease is a rare disease characterized by either one single hyperplastic lymph node confined to an anatomic site in the unicentric type or generalized lymphadenopathy in the multicentric type. The most common site of Castleman's disease is the thorax. Castleman's disease of the pancreas is extremely rare. The treatment for Castleman's disease of the unicentric type is surgery. In the multicentric type, the treatment remains controversial, and is usually composed of variable chemotherapeutic regimens. We report a case of unicentric Castleman's disease in the pancreas that was treated successfully by surgery. A 29-year-old female presented with intermittent watery diarrhea for six months. A computed tomography scan revealed one smooth, homogeneous, and well-demarcated tumor in the pancreatic body. The tumor was excised smoothly at laparotomy and the histologic findings were compatible with Castleman's disease. The postoperative course of the patient was uneventful, with gradual improvement of the symptoms. There was no evidence of recurrence at one- year follow-up. Only six cases of Castleman's disease in the pancreas have been reported in the English literature. Although rare cases of unresectable pancreatic Castleman's disease do exist, most patients with unicentric Castleman's disease of the pancreas can be treated successfully by complete excision of the lesion. When total excision can be obtained, the prognosis is excellent.
延伸閱讀
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