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The Prognostic Significance of Pathologic Characteristics of Breast Cancer Patients in Taiwan

乳癌的病理特徵在預後的重要性

摘要


To investigate the prognostic significance of pathologic characteristics of breast cancer patients, we retrospectively studied 514 patients with operable cancer from 1978 through 1987. The mean age of the patients was 50.2±12.4 years. Tumor sizes ranged from 0.7 to 13.0 cm, with a mean size of 4.26±2.4 cm. Axillary node metastases were found in 56.4% of the patients. Univariate analysis on the survival rate revealed that the number of positive nodes, tumor size, lymphatic permeation, tumor necrosis, histologic type, histologic grade, and age were significant prognostic factors. Multivariate Cox regression analysis showed that the number of positive nodes (ρ<0.00005), histologic grade (ρ=0.0002), and tumor size (ρ=0.0108) were independent prognostic factors. Our study confirms the importance of pathologic characteristics in predicting the prognosis of breast cancer patients.

關鍵字

乳癌 病理 預後

並列摘要


To investigate the prognostic significance of pathologic characteristics of breast cancer patients, we retrospectively studied 514 patients with operable cancer from 1978 through 1987. The mean age of the patients was 50.2±12.4 years. Tumor sizes ranged from 0.7 to 13.0 cm, with a mean size of 4.26±2.4 cm. Axillary node metastases were found in 56.4% of the patients. Univariate analysis on the survival rate revealed that the number of positive nodes, tumor size, lymphatic permeation, tumor necrosis, histologic type, histologic grade, and age were significant prognostic factors. Multivariate Cox regression analysis showed that the number of positive nodes (ρ<0.00005), histologic grade (ρ=0.0002), and tumor size (ρ=0.0108) were independent prognostic factors. Our study confirms the importance of pathologic characteristics in predicting the prognosis of breast cancer patients.

並列關鍵字

Breast cancer pathology prognosis

被引用紀錄


蔡欣芸(2008)。乳癌核心測量在病人層次的指標遵從度分析及其與病患存活之相關性研究〔碩士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2008.02813
蔡翠珍(2007)。乳癌病人疾病管理與治療結果之分析-以論質計酬試辦計畫參與醫院為例〔碩士論文,臺北醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0007-0602200715160200
劉育呈(2013)。共線性問題下癌症患者存活影響因素之分析〔碩士論文,國立臺北科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0006-2407201312045300

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