Fleet PHOSPHO-SODA引起的高磷血低鈣血症，以類中風的半側麻痺表現：一病例報告

Sodium Phosphate Induced Hyperphosphatemia, Hypocalcemia-A Case Report

吳明修(Ming-Hsiu Wu) ； 陳志州(Jyh-Jou Chen) ； 黃國清(Kuo-Ching Huang)

《內科學誌》 16卷5期 (2005/10) Pp. 236-240

https://doi.org/10.6314/JIMT.2005.16(5).05

摘要

Fleet PHOSPHO-SODA目前為一種常用的瀉劑，最常使用的情形為大腸鏡檢查前的大腸清潔準備，但是也常用於治療排便不良的情況。在台灣或是國外病人也可於藥房購買此項藥品。雖然是一安全性甚高的藥物，然而也有一些副作用，甚至致死的病例。而這些是處方這個藥物的醫師必須要瞭解的。最為重要的併發症為電解質的不平衡與脫水，水分的缺乏可能進一步演變成腎衰竭。而高磷低鈣血症是其中最為明顯的合併症。我們報告一例78歲的婦女，於服用90毫升未經稀釋的Fleet PHOSPHO-SODA後出現類似中風的半側麻木症狀。實驗室檢查出現嚴重的高磷血症，與低鈣血症。當高磷血症與低鈣血症經由治療而校正為正常後，類似中風的半側麻木症狀旋即回覆正常。

關鍵字

Fleet PHOSPHO-SODA ； 末期腎臟衰竭 ； 高磷血症 ； 低鈣血症 ； 半側麻痺

並列摘要

Fleet PHOSPHO-SODA is a laxative commonly used by many physicians for preparation of colonoscopy. Also, it is used frequently for treatment of constipation. Patients and their families can even buy it over the counter. Although it is relatively save, it does cause some adverse side effects which are so significant that physicians who prescribe it and the general public who buy it over the counter should be aware of. Volume depletion and electrolyte disturbance are commonly mentioned. Intravascular volume depletion might deteriorate renal function, and cause overt acute renal failure. Nevertheless, the most important and drastic side effects are electrolyte disturbance-hyperphosphatemia and hypocalcemia. We present a 78-year-old lady with hemiparesthesia, mimicking stroke after oral intake of undiluted Fleet PHOSPHO-SODA, 90 ml. Later, laboratory data revealed severe hyperphophatemia and hypocalcemia. Hemiparesthesia resolved completely after correction of hyperphophatemia and hypocalcemia.

並列關鍵字

Fleet PHOSPHO-SODA ； End stage renal disease ； Hyperphophatemia ； Hypocalcemia ； Hemiparesthesia