In a cold store, the distribution of temperature that could affect qualitiesof product is influenced by the flow patterns directly. Therefore, it is very important to describe and predict the flow patterns in a cold store. In our previous paper the flow patterns and temperature distributions are analyzed with data measured in a full scale prefabricated cold store. Numerical approaches are discussed in this study to investigate the air flow characteristics in a prefabricated cold store, and results are compared with experimental data that obtained by measurements with a three dimensional ultrasonic anemometer. Modeling of the airflow and heat transfer in the clod store is completed by FLOW-3D computer package. Mean airflow patterns and emperature distributions in various sections of the cold store are discussed indetail. Numerical simulation shows good agreement in both of airflow patterns and temperature distribution. The current founding is not only significant for understanding the airflow behavior in cold stories but also important in improving the modeling method for airflow predictions.