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小唾液腺淋巴上皮瘤樣癌

Lymphoepithelioma-like Carcinoma of the Minor Salivary Gland

摘要


根據文獻索引,口腔及口咽內淋巴上皮瘤樣癌在全世界已報導病例中已屬少見,其中源發於小唾液腺之淋巴上皮瘤樣癌更是罕見,只有4例。本院在2001年1月有1名53歲男性病人,因為口腔頰部腫塊至本院門診求診,理學檢查發現右側口腔頰部黏膜下有一無痛性腫塊,於是安排手術切除,病理報告發現為淋巴上皮瘤樣癌,病人術後接受放射線治療。追蹤18個月至今,情況良好,無復發跡象產生。

並列摘要


Lymphoepithelioma-like carcinoma of the oral cavity is rare, and diagnosis is difficult even when presented with clinical and radiological findings. In the world literature, only four cases have been described in which the minor salivary gland was affected. A 53-year-old man presented to our hospital with a firm, nontender mass in the right buccal region. The mass was submucosal and about 2cm in diameter and cervical lymph nodes were not palpable. The nasopharyngeal mucosa was intact when examined sinoscopically and showed no evidence of tumor involvement. An intraoral wide excision of the buccal tumor was performed. Tissue pathology provided the diagnosis of lymphoepithelioma-like carcinoma of the minor salivary gland and tumor cells were also found to be positive for EBER using in situ hybridization. Postoperative radiotherapy was administered and there was no evidence of recurrence during an 18 month follow-up period.

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