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Technetium-99m-Pyrophosphate Muscle Scintigraphy in Polymyositis: A Case Report

鎝-99m-焦磷酸鹽在多發性肌肉發炎病人的應用:個案報告

摘要


不明原因發炎性肌肉病變是一大群後天性且可治癒性的疾病,所以臨床上對這個疾病的診斷是很重要但卻又是很困難的。本病例是一位32歲女性,從2003年開始感受到近端肢體肌肉無力,並且有越來越嚴重的趨勢,因為臨床症狀和實驗室數據懷疑為多發性肌肉發炎,肌肉切片後確定是肌肉發炎,在藥物治療的過程疾病仍是起伏不定。然而,肌肉切片是一項具侵犯性的檢查,不能重複實行來確診。而鎝-99m-焦磷酸鹽(PYP)肌肉閃爍攝影在評估肌肉病變的範圍和疾病活性有幫助,而且可以對肌肉切片提供一項客觀的定位方法。

並列摘要


Idiopathic inflammatory myopathies represent the largest group of acquired and potentially treatable disorders. Clinical diagnosis is very important but difficult for these disorders. We present a case of 32-year-old woman who suffered from progressive weakness of the proximal muscles since 2003. Clinical presentations and laboratory data showed suspicious diagnosis of polymyositis and muscle biopsy result is compatible with myositis. Her symptoms still fluctuated even under the serial treatment program. However, muscle biopsy is an invasive method, which could not repeat for disease activity. We observe that (superscript 99m)Tc-pyrophosphate (PYP) muscle scan may be helpful in evaluating the extent of myopathy and disease activity and may be an objective guide for muscle biopsy.

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