Malignant mesothelioma is a rare tumor with a high prevalence in people who are exposed to asbestos. We present a case of a 66-year-old male complaining of progressive shortness of breath for two months. A chest X-ray and chest computed tomography (CT) scan showed a right side massive pleural effusion and pleura thickening. A pleural biopsy confirmed the diagnosis of malignant mesothelioma. Review of the patient's history showed that he worked in a cathode ray tube factory for 30 years and wore asbestos-lined clothing for protection against the heat generated by the cathode ray tubes. Other co-workers have also been diagnosed with malignant mesothelioma. This case serves as a reminder of the dangers of asbestos exposure to one's health and how a history of exposure can facilitate in the diagnosis of this rare tumor.