Primary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma

上頷竇扁平細胞癌之放射治療結果

許智捷(Chih-Chiech Hsu) ； 雷德(Louis Tak Lui) ； 鍾娜娜(Na-Na Chung) ； 丁禮莉(Lai-Lei Ting) ； 邵文逸(Wen-Yi Shau)

《放射治療與腫瘤學》 5卷3期 (1998/09) Pp. 163-170

https://doi.org/10.6316/TRO/199805(3)163

摘要

目的：評估上頷竇癌用不同治療方後的結果。材料與方法：從1977至1991年61個上頷竇扁平細胞中，有11個病人(18%)是T3，50個病人(82%)是T4。其中18個病人只作放射治療，32個病人術後追加放射治療，11個病人合併放射治療，竇造口術及動脤內注射化學治療。結果：以上三組病人五年存活率分別為5.6%,34.4%及54.5，具有明顯統計差別。在診斷時有淋巴轉移的病人，其五年存活率較無淋巴轉移病人明顯偏低（7.1%比36.2%）。多變數分析得出性別，治療方式，淋巴分期為顯著的預後因子。結論：合併治療比只作放射治療有較好的五年存活率。

關鍵字

放射治療 ； 合併治療 ； 上頷竇 ； 扁平細胞癌

並列摘要

Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p＜0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.

並列關鍵字

Radiotherapy ； Combined treatment ； Maxillary sinus ； Squamous cell carcinoma