Objective: We report a schizophrenic woman who developed new-onset diabetes mellitus (DM) and hyperlipidemia after having taken clozapine for three years. Case Report: A 39-year-old Hakka woman with chronic schizophrenia who had multiple hospitalizations for acute psychiatric symptoms, had been treated with flupenthixol, sulpiride, clopenthixol, risperidone, flupenthixol depot injection, and 20 treatments with bilateral electroconvulsive therapy (ECT). These treatments had not caused DM or hyperlipidemia. However, her treatment was later modified and clozapine (300 mg/d) was started. Although the addition of clozapine improved her psychotic symptoms, she developed new-onset DM and hyperlipidemia three years later. At last follow up in April of 2005, she required antidiabetic and antilipid medications for controlling DM and hyperlipidemia. Conclusion: The findings of this case stress the importance of early recognition of developing hyperglycemia and hyperlipidemia when schizophrenic patients are treated with clozapine.
為了持續優化網站功能與使用者體驗,本網站將Cookies分析技術用於網站營運、分析和個人化服務之目的。
若您繼續瀏覽本網站,即表示您同意本網站使用Cookies。