- 期刊
- OpenAccess
Antiseptic Effect of Betel Quid Extract on Lip Mucosal Wound of male Wistar (Rattus novergicus) Rats
摘要
Antiseptic is commonly used in dentistry practices, but some antiseptics have side effects such as allergy. Therefore, natural substances are developed as substitute, i.e betel quid which consisted of betel leaf, areca nut, gambier, and mineral slaked lime. The aim of this study was to determine antiseptic effect of betel quid extract on lip mucosal wound of male Wistar (Rattus norvegicus) rats. This study was true experimental in vivo. Thirty rats were divided into five groups; three groups were treated with betel quid extract ointments at concentration of 5%, 10% and 20%, one group was positive control (hyaluronic acid) and last group was negative control (placebo). One-mm diameter of wound was made on lower lip mucosa of rats with cylinder diamond bur. All wounds were swabbed before and after treatment, and the number of bacterial colonies grown in agar plates were counted. The results showed that there was significant decrease of bacterial colony numbers for respective groups, except for negative control (p ＜ 0.05). Ointment containing 20% betel quid extract had antiseptic effect similar to 0.2% hyaluronic acid. It can be concluded that betel quid extract had antiseptic effect on lip mucosal wound.
延伸閱讀
- Liu, A. C., Mu, J. Y., & Pi, W. P. (1964). Respiratory Quotient of the Rat under Basal Conditions. The Chinese Journal of Physiology, 19(2), 221-235. https://www.airitilibrary.com/Article/Detail?DocID=03044920-196406-19-2-221-235-a
- 陳立典（2004）。The Inhibitory Effects of Botulinum Neurotoxin on Inflammation Induced by Mustard Oil Injection into Rat’s Hind Paw〔碩士論文，臺北醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0007-1704200714541731
- Ufelle, S. A., Ukaejiofo, E. O., Neboh, E. E., Achukwu, P. U., Ghasi, S., Ikekpeazu, E. J., & Maduka, I. C. (2011). The Effect of Crude Methanolic Leaf Extract of ＂Bryophyllum pinnatum＂ on Some Haematological Parameters in Wistar Rats. Asian Journal of Medical Sciences, 3(3), 121-124. https://www.airitilibrary.com/Article/Detail?DocID=20408773-201106-201510300010-201510300010-121-124
- 謝典華（2003）。Effects of betel quid ingredients on human oral mucosal fibrosis and carcinogenesis〔博士論文，高雄醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0011-0707200816042179
- 林文川、柯裕仁、吳岳文（2000）。Effects of 28-Day's Repeated Oral Administration of Crude Aqueous Extracts of Glycine Tomentella Hayata on Rats。中醫藥雜誌，11(4)，205-215。https://doi.org/10.6940/JCM.200012_11(4).06