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A Case Report Successful Thrombolysis for Massive Pulmonary Embolism: Rapid Low-Dose Intra-Embolic Therapy

快速以低劑量的血栓溶解劑直接注入肺栓塞治療獲得成功之病例報告

摘要


術後發生大量的肺栓塞的病人,因為考量術後有出血的傾向,而無法採用傳統的血栓溶解治療。針對這類大量血栓造成右心衰竭的危急病患,可採導管或外科手術直接剝離血栓。但是這類手術通常有很高的風險,而且也不是每家醫院都能立即施行。我們報告一個入院實行子宮切除手術的病患,不幸術後發生大量肺栓塞並造成右心衰竭。儘速以低劑量的血栓溶解劑直接注入肺栓塞處治療,能快速改善病患的血行動力,最後成功恢復且無併發症。

並列摘要


Management of postoperative acute massive pulmonary embolism (PE) presents a dilemma because recent surgical procedure is usually considered an absolute contraindication for thrombolysis. In these patients, catheter or surgical embolectomy are helpful for rapidly reversing right ventricular failure. However, pulmonary embolectomy itself has a high mortality and may not always be available. We report the successful use of low-dose intra-embolic thrombolysis for acute massive PE after abdominal total hysterectomy. The infusion of low-dose urokinase produced an immediate improvement in the patient's hemodynamic state. The patient tolerated the thrombolytic therapy well, without hemorrhage or other complications and made a successful recovery.

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