Neurofibroma in the Left Mandible: A Case Report

發生於左側下頜骨的神經纖維瘤：病例報告

陶謙(Qian Tao) ； 王一(Yi Wang) ； 鄭超群(Chao-Qun Zheng)

《The Kaohsiung Journal of Medical Sciences》 26卷4期 (2010/04) Pp. 217-221

摘要

以下闡述一個極其罕見的發生在左側下頜骨相對孤立的神經纖維瘤，同時並無I型神經纖維瘤的家族病史。腫瘤的組織病理學與免疫組織化學分析顯示S-100蛋白成陽性。Vim，HMB45和HHF35成陰性表達。腫瘤細胞呈梭形，並且呈編制狀排列，生長活躍。典型的神經纖維瘤特徵是以伸長的細胞核和不充分的細胞質組成的增大的神經纖維束。這篇報告我們主要強調在無任何I型神經纖維瘤病的特徵下發生在下頜骨同時相對孤立的神經纖維瘤。

關鍵字

診斷 ； 下頜骨 ； 神經纖維瘤

並列摘要

We report a rare case of isolated neurofibroma arising in the left mandible without family history of neurofibromatosis type 1. The tumor was histopathologically analyzed and an immunohistochemical panel comprising S-100 protein was performed. Vim, HMB45, and HHF35 were negative. The tumor cells were fusiform in shape, arranged in a plexiform manner, and grew actively. Features typical of neurofibroma, including an enlarged nerve fascicle composed of elongated nuclei and scant cytoplasmic cells, were identified. Our study suggest that neurofibroma can occur in the jaw as an isolated benign tumor in patients without other features of neurofibromatosis type 1.

並列關鍵字

diagnosis ； mandible ； neurofibroma