Peritoneal Metastasis in Osteosarcoma: Report of One Case

骨癌併發腹膜轉移：一病例報告

葉淑寧(Shu-Nin Yeh) ； 盧孟佑(Meng-Yao Lu)

《Acta Paediatrica Taiwanica》 46卷4期 (2005/08) Pp. 230-234

https://doi.org/10.7097/APT.200508.0230

摘要

我們報告一件骨癌腹腔膜轉移的案例。依骨癌的轉移部位，以腹腔膜表現者是較罕見的。一位患有股骨骨癌的十四歲大男孩在接受手術切除及完成化學治療之後，在初診後二十七個月出現一個無法被切除的肺部轉移。當他接受挽救性化療時，在第三十八個月又發現惡性腹積水及腹腔膜轉移。兩個月後他因此而過世。這是全世界被報告的第六例因骨癌而產生的腹腔膜轉移，也是目前最年輕的一位病患。我們描述這位男孩的病情及治療並回顧文獻上過去的病例。以骨癌病患來說，如出現持續的腹部徵兆應提早做腹部電腦斷層及腹水檢查來診斷腹部轉移。隨著治療的進步，我們也許會看到更多的少見部位的轉移。

關鍵字

骨癌 ； 腹膜 ； 轉移

並列摘要

We describe a rare case of peritoneal metastasis in osteosarcoma. A 14-year-old boy was diagnosed with osteosarcoma of the femur. Although initial treatment with surgical resection and chemotherapy was successful, a large inoperable pulmonary metastasis was detected 27 months after diagnosis of the primary tumor. At 38 months, whilst still receiving salvage chemotherapy, malignant ascites with peritoneal metastasis was detected. The patient died two months later from disease progression. This is probably the 6(superscript th) case and youngest patient with peritoneal metastasis of osteosarcoma reported in the literature. For early diagnosis, patients with a history of osteosarcoma having persistent abdominal symptoms or signs should be offered a CT scan of the abdomen, and examination of the ascitic fluid when present. With advances in treatments, unusual sites of metastasis may become more prevalent.

並列關鍵字

osteosarcoma ； peritoneum ； metastasis