This paper examines the use of BCG vaccination in Taiwan in the 1950s and 1960s. It is taken as an example to explain how tuberculosis prevention in Taiwan was connected to the international standard. The vaccination project was based on the WHO standard and performed as a small scale trial in certain regions of Taiwan. An appropriate method had been developed prior to the implementation of the vaccination plan for the whole population. This paper attempts to discuss global vaccination through the following aspects: 1. When BCG arrived in Taiwan, the way in which it moved from a laboratory study, through small field trials and centers, and to the compulsory vaccination of the population; 2. the techniques of BCG vaccine production in Taiwan; 3. the training of the BCG vaccinators; 4. concerns and reservations about the BCG vaccine. Of these aspects, special consideration is given to the delineation of the process through which a western preventive technique was introduced and implemented in the Taiwanese society.