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Detection of Differentially Expressed Genes in Small Sets of cDNA Microarrays
並列摘要
Methods for testing the equality of two means are of critical importance in many areas of applied statistics. In the microarray context, it is often necessary to apply this kind of testing to small samples containing no more than a dozen elements, when inevitably the power of these tests is low. We suggest an augmentation of the classical t-test by introducing a new test statistic which we call ”bio-weight.” We show by simulation that in practically important cases of small sample size, the test based on this statistic is substantially more powerful than that of the classical t-test. The power computations are accompanied by ROC and FDR analysis of the simulated microarray data.
被引用紀錄
林明鴻（2016）。翻轉教室教學法融入使用者經驗設計課程之個案研究〔碩士論文，淡江大學〕。華藝線上圖書館。https://doi.org/10.6846/TKU.2016.00270
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陳佑杰（2005）。低價機器視覺系統之硬體式影像擷取技術發展〔碩士論文，淡江大學〕。華藝線上圖書館。https://doi.org/10.6846/TKU.2005.00728
Chen, Y. H. (2011). 應用於影像壓縮之高效能轉換核心 [doctoral dissertation, National Tsing Hua University]. Airiti Library. https://doi.org/10.6843/NTHU.2011.00700
CHAUDHURI, R. (2010). New Pathway Towards the Synthesis of Dibenzo[g,p]chrysenes bearing various Functionalities and Studies of their Photophysical and Electronic Properties & Transition Metal Catalyzed Organic Transformations for the Synthesis of Functionalized Carbocyclic Frameworks [doctoral dissertation, National Tsing Hua University]. Airiti Library. https://doi.org/10.6843/NTHU.2010.00193
延伸閱讀
- Wong, T. Y. (2005). Molecular characterization of IBDV-induced apoptosis in vitro using cDNA microarrays [master's thesis, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200014668
- Ma, T. H. (2008). Identification of the Gene Signatures in Microarray Data by CID [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2008.01692
- Chen, S. S. (2009). Prediction analysis for gene expression microarrays using a reference set and simple t test [master's thesis, National Chiao Tung University]. Airiti Library. https://doi.org/10.6842/NCTU.2009.00508
- 石貴中（2004）。Prediction of Cancerous Genes using cDNA Microarray Data and Gene Regulation Relationship〔碩士論文，亞洲大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0118-0807200916271795
- Wei, C. C. (2014). Gene expression profiling and functional genomics by microarray analysis [doctoral dissertation, National Tsing Hua University]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0016-2105201414244216