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摘要


子宮肌瘤廣泛的影響了生育年齡的婦女,可能是源於遺傳和環境因素。子宮肌瘤的症狀包括經痛或經血過多,干擾日常生活,和生育能力受損。由於高流行率和增加相關的治療成本,子宮肌瘤的直接和間接成本對於醫療保健系統和個別患者兩者都是重要的疾病。特殊患者群體-例如黑人女性,尋求保持生育能力的女性和患有無症狀肌瘤的女性需要多種診斷方法和特殊治療需求選項。對於無症狀的子宮肌瘤患者,僅需定期門診追蹤,對於有症狀的肌瘤,第一線治療乃是以藥物來治療。本文將介紹現今對於子宮肌瘤藥物治療的建議-非類固醇類抗發炎止痛藥、斷血炎、黃體素、避孕藥、選擇性黃體素受體調節劑(selective progesterone receptor modulator, SPRM)與促性腺激素釋放激素促進劑(gonadotropin releasing hormone agonist)。對於子宮肌瘤的新藥物-促性腺激素釋放激素拮抗劑(gonadotropin releasing hormone antagonist),目前已有第三期臨床研究報告表明有顯著的治療效果,未來對於罹患子宮肌瘤又不想接受手術的婦女也是一個福音。

參考文獻


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