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表淺CD34陽性纖維母細胞瘤之病理表現

摘要


表淺CD34陽性纖維母細胞瘤(superficial CD34-positive fibroblastic tumor, SCPFT)在第5版世界衛生組織軟組織與骨腫瘤分類(WHO classification of Soft Tissue and Bone tumors, 5^(th) edition)中已確立為一個新的軟組織腫瘤,常生長於下肢表淺軟組織。儘管組織學上有相當程度的細胞多形性(pleomorphism),手術切除後局部復發以及轉移的風險都很低,其重要性在於與其他形態學相似但惡性度較高的軟組織腫瘤做鑑別診斷。

參考文獻


Carter JM, Weiss SW, Linos K, et al. Superficial CD34-positive fibroblastic tumor: report of 18 cases of a distinctive low-grade mesenchymal neoplasm of intermediate(borderline) malignancy. Modern Pathology 2014;27:294-302.
Salah HT, D'Ardis J A, Baek D, et al. Superficial CD34-positive fibroblastic tumor(SCPFT): A review of pathological and clinical features. Ann Diagn Pathol 2022;58:151937.
Florek AG, Krunic AL, Amin SM, et al. Superficial CD34-Positive Fibroblastic Tumor Successfully Treated With Mohs Micrographic Surgery. Dermatologic Surgery 2018;44:313-5.
Puls F, Pillay N, Fagman H, et al. PRDM10-rearranged Soft Tissue Tumor: A Clinicopathologic Study of 9 Cases. Am J Surgical Pathol 2019;43:504-13.
Yamaga K, Fujita A, Osaki M, et al. Detailed analysis of a superficial CD34-positive fibroblastic tumor: A case report and review of the literature. Oncol Lett 2017;14:3395-400.

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