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  • 期刊

中藥強化阿斯匹靈抗性患者的抗血栓與預防中風效果

Traditional Chinese Medicine Show the Effect of Reducing Thrombosis and Stroke Prevention for Patients with Aspirin Resistance

摘要


近幾年中醫界開始注重中西藥併用的問題,最常被提到的就是與抗血栓西藥有交互作用,包括人參、丹參、當歸、川芎都常常被點名。除了小心以外,有沒有可能利用中西藥合併加強效果呢?臨床研究告訴我們,對於阿斯匹靈抗血栓效果不佳的病人,合併丹參等活血藥治療可以更有效的抑制血栓形成、改善中風症狀、減少再次中風機會,而且並不會增加異常出血的風險。阿斯匹靈與丹參等藥物同樣具有抗血栓的效用,合併使用當然要注意,但並不能想當然耳的推測併用一定會增加出血風險,還是要回歸到臨床研究,用科學證據評估療效與風險。

關鍵字

Aspirin 阿斯匹靈 中醫 丹參 抗血栓 血小板

並列摘要


In recent years, Chinese medicine practitioners began to pay attention to the combination of Chinese and Western medicine. The most common is the interaction between traditional Chinese medicine and antithrombotic drugs, including ginseng, Salvia, Angelica, Chuanxiong and so on. Clinical research tells us that when the patient aspirin antithrombotic effect is weak, Western medicine combined Salvia and other blood drug treatment can be more effective in inhibiting thrombosis, improve stroke symptoms, reduce the chance of another stroke, and does not increase the risk of abnormal bleeding. Aspirin and Salvia and other drugs also have the anti-thrombotic effect. However, Chinese medicine practitioners still need to pay attention to the clinical use of traditional Chinese medicine and western antithrombotic medicine, but it can't be judged that the combined use will undoubtedly increase the bleeding risk.

參考文獻


Zheng AS, Churilov L, Colley RE, Goh C, Davis SM, Yan B. Association of aspirin resistance with increased stroke severity and infarct size. JAMA Neurol. 2013 Feb; 70 (2): 208-13. doi: 10.1001/jamaneurol.2013.601.
Chen H, Shen Z, Chen J, Zhang H, Chen X. Chinese Herbal Medicine for Aspirin Resistance: A Systematic Review and Meta-Analysis.PLoS One. 2016 May 6; 11 (5): e0154897. doi: 10.1371/journal.pone.0154897. eCollection 2016.
Hovens MM, Snoep JD, Eikenboom JC, van der Bom JG, Mertens BJ, Huisman MV. Prevalence of persistent platelet reactivity despite use of aspirin: a systematic review. Am Heart J. 2007 Feb; 153 (2) : 175-81.

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