To of applying anti-tumor formula to treat malignant tumors. The anti-tumor formula was developed on the basis of Tumor-dissolving pill (scorpion, bombyx batryticatus, beehive), which was created by Professor Zhu liangchun, a national masters of traditional Chinese medicine at the first session and specialized in treating malignant lymphoma. Clinical verification showed that this formula had good effect in treating various malignant tumors. The formula can be used together with other formulas based on clinical syndrome differentiation. And it can be used directly by adding medicinal guide herbs so as to reach the targeting affected area.