Natsume Sōseki (1867 ~ 1916) is often considered the greatest writer in modern Japanese history and is best-known for his novels Kokoro, Botchan, I Am a Cat, Sanshiro and his unfinished work Light and Darkness. He was also a scholar of British literature and composer of haiku, kanshi, and fairy tales. The novel "Kokoro" (literally means heart), is divided into three parts. In the second part, "My Parents and I", the narrator took care of his father with chronic kidney disease (CKD), through the reading, we could recognize how the people treat the patients with CKD in Japan one hundred years before.