- 期刊
Chlorination of Methyl 2-Methylbenzoate to Methyl 2-(chloromethyl) Benzoate
2-甲基苯甲酸甲酯氯化反應之研究
摘要
Various free radical initiators, benzoyl peroxide (BPO), azobisisobutyronitrile (AIBN), and UV light (315-400nm) were used to study the optimum conditions for obtaining methyl 2-(chloromethyl) benzoate via chlorination. Experimental results showed that at 70℃, sparging chlorine gas (1.1 moles) into methyl 2-methylbenzoate produced a 65-67% yield of methyl 2-(chloromethyl) benzoate. Different free radical initiators showed no effects on the distribution of chlorinated products, but did impact the reaction rates: UV＞BPO＞AIBN.
關鍵字
無資料並列摘要
Various free radical initiators, benzoyl peroxide (BPO), azobisisobutyronitrile (AIBN), and UV light (315-400nm) were used to study the optimum conditions for obtaining methyl 2-(chloromethyl) benzoate via chlorination. Experimental results showed that at 70℃, sparging chlorine gas (1.1 moles) into methyl 2-methylbenzoate produced a 65-67% yield of methyl 2-(chloromethyl) benzoate. Different free radical initiators showed no effects on the distribution of chlorinated products, but did impact the reaction rates: UV＞BPO＞AIBN.
延伸閱讀
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