近視性黃斑部病變是高度近視併發症中最嚴重之一。而這病變又首眼軸延長、近視加深及年齡老化有關。視神經盤半月斑又被認為是眼底後極部退化的早期徵侯。所以評估兩者之間的關系有助於了解黃斑部病變的病程。由台大醫院高度近視門診共收集993位高度近視病人,結果發現半月斑大於一個視神經盤寬度之機率在軸長大於29 mm,近視超過-15 D及年齡大於40歲組明顯比較高。同樣地,黃斑部病變超過D1(有Lacquer crack以上)有69.4%其半月斑大於一個視神經盤寬度。而黃斑部有廣泛性萎縮(超過D2以上)有78.5%其半月斑大於一個視經盤寬度。若以半月斑大小顧並個視經盤寬度為準,約可診斷出75.8%有D1以上之變化,56.4%有D2以上之變化。假如同時以半月斑大小大於一個視神經盤寬度加上眼軸長大於29 mm為準,可診斷86.5%之病人有D1以上之變化。若再加上年齡40歲以上,更可以診斷出94.3%以上之病人有D1以上之其黃斑部退化。所以,半月斑大小可能可以當作近視性黃斑部退化之預測因素。(慈濟醫學1996; 8: 205-211)
Myopic maculopathy is one of the most severe complications of high myopia. The severity correlates with the increase of axial length, refractive error and age. Optic disc crescent formation was suggested to be an early sign of the degeneration of the posterior pole. Thus, evaluating the correlation between myopic maculopathy and the size of the disc crescent is needed. Analysis of 993 high myopic patients form the high myopic clinic at National Taiwan University hospital (NTUH)showed that the size of the disc crescenet was correlated with an increase in axial length and refractive error. The incidence of disc crescent greater than one disc diameter (DD) was also higher in groups with axial length longer than 29.0 mm, refractive error over -15.0 D and/or age older than 40 years. As well, 69.4% of patients with myopic maculopathy more severe than D1 had disc crescents larger than 1 DD; 78.5% of patients with myopic maculopathy more severe than D2 had disc crescents larger than 1 DD. If only the disc crescent larger than 1 DD was considered, 75.8% of the patients had D1 myopic maculopathy or more, and 56.4%of the patients had D2 myopic maculopathy or more. If both conditions with axial length over 29.0mm and disc crescent larger than 1 DD were considered together, then 86.5% of the patients had D1 myopic maculopathy or more. Further, if all of the conditions with axial length over 29.0 mm, subject’s age older than 40 years and disc crescent larger than 1 DD were considered together, 94.3% of the patients had D1 or more myopic maculopathy. Therefore, the size of the disc crescent could be one of the factors to predict the possibility of myopic maculopathy. (Tzu Chi Med J 1996; 8: 205-211)