背景:雖然賓州大學嗅覺識別檢查是世界上常用的嗅覺檢查方法之一,它使用在美國以外的國家仍有文化差異的問題,因此著者將賓州大學嗅覺識別檢查修正為賓州大學嗅覺識別檢查繁體中文版。本研究嚐試建立賓州大學嗅覺識別檢查繁體中文版正常值,以供臨床使用。方法:從2010年3月至2013年4月收集嗅覺正常男女受測者。他們均經由病史及理學檢查來排除罹患鼻及鼻竇炎,也排除罹患鼻息肉或腫瘤。他們再接受酚基乙基乙醇氣味查覺閾值試驗來檢查嗅覺功能,如果閾值大於-6則被排除在本研究之外。共收集20至29歲、30至39歲、40至49歲、50至59歲、60至69歲、70至79歲不同年齡層男女受測者各30名接受賓州大學嗅覺識別檢查繁體中文版測試其嗅覺功能。以分數分布圖的第十個百分位數定義為正常值。結果:20至29歲年齡層受測者的賓州大學嗅覺識別檢查繁體中文版分數在男性平均為32.2,女性為33;30至39歲年齡層在男性平均為33.07,女性為32.87;40至49歲年齡層在男性平均為31.8,女性為32.8;50至59歲年齡層在男性平均為30.23,女性為30.33;60至69歲年齡層在男性平均為28.07,女性為27.57;70至79歲年齡層在男性平均為25.2,女性為25.13。賓州大學嗅覺識別檢查繁體中文版分數在50歲後不論男女均呈現逐漸下降,但分數在男女之間並無明顯差異。在20至49歲男性受測者的第十個百分位數為29,在50至79歲為22,在20至49歲女性受測者的第十個百分位數為29,在50至79歲為21。結論:本研究首次建立賓州大學嗅覺識別檢查繁體中文版正常值,方便它在本土使用。
BACKGROUND: Although the University of Pennsylvania Smell Identification Test (UPSIT) is the most widely used smell test in the world, it has cultural biases. The author translated UPSIT into a traditional Chinese version of the UPSIT. This study tried to establish the normative data.METHODS: Subjects with normal smell function were included between March, 2010 and April, 2013. They did not suffer from rhinosinusitis, nasal polyps or nasal tumor by history and physical examination. They received phenyl ethyl alcohol odor detection threshold test. If their thresholds were above -6, they were excluded from the study. Thirty male and female subjects were collected from each of six 10-year intervals (20 to 29 years old, 30 to 39 years old, 40 to 49 years old, 50 to 59 years old, 60 to 69 years old, and 70 to 79 years old). They received a test with a traditional Chinese version of the UPSIT. The score at the tenth percentile has been defined to separate hyposmia from normosmia,.RESULTS: The mean score was 32.2 for males and 33 for females in the age interval of 20 to 29, was 33.07 for males and 32.87 for females in the age interval of 30 to 39, was 31.8 for males and 32.8 for females in the age interval of 40 to 49, was 30.23 for males and 30.33 for females in the age interval of 50 to59, was 28.07 for males and 27.57 for females in the age interval of 60 to 69, was 25.2 for males and 25.13 for females in the age interval of 70 to 79. The score decreased after the age of 50 whether in the male or female subjects, but the score was not significantly different between males and females. The male score at the tenth percentile was 29 for ages from 20 to 49 years and 22 for ages from 50 to 79 years. The female score at the tenth percentile was 29 for ages from 20 to 49 years and 21 for ages from 50 to 79 years.CONCLUSIONS: This study established the normative data of the traditional Chinese version of the UPSIT to promote its use in Taiwan.