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瀰漫性原因不明性過度骨化:病例報告

Diffuse Idiopathic Skeletal Hyperostosis: A Case Report

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摘要


瀰漫性原因不明性過度骨化(diffuse idiopathic skeletal hyperostosis, DISH) 常見於中老年人,但常為臨床醫師所忽略。DISH的特徵為脊椎前縱韌帶(anterior longitudinal ligament) 及周邊關節肌腱、韌帶的骨化(ossification) 及著骨點病變(enthesopathy),而真正的病因仍未確定。因DISH的高盛行率但低診斷率,且臨床上常造成患者慢性疼痛僵硬甚至少數患者會合併嚴重的併發症,而診斷上易與脊椎退化性關節炎(spondylosis)、僵直性脊椎炎(ankylosing spondylitis, AS)等疾病混淆,因此值得我們注意。本文報告一位71歲之男性,因慢性肩痛及背痛至門診求診,文中描述病患的臨床症狀、診斷及治療,並回顧相關文獻資料,以做為臨床醫師診斷及治療之參考。

並列摘要


Diffuse idiopathic skeletal hyperostosis (DISH) is a common disorder in middle-aged and elderly patients but often ignored. It is characterized by calcification and ossification of the spinal ligaments, as well as entheseal ossification within extraspinal sites. The etiology of DISH is still unknown. It can result in chronic pain and stiffness and occasionally severe disability. It often mimiks with spondylosis and ankylosing spondylitis. We report a 71-year-old male patient who suffered from chronic back and shoulders pain for many years. DISH was diagnosed after a series of examinations. The symptoms of the patient were improved temporarily after medical treatments and physical therapy. The purposes of this case report are to state the symptoms, signs, diagnosis, differential diagnoses, and treatments of DISH, as well as to remind all the clinicians of this common disease.

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