A 58-year-old female with a history of stage IV esophageal cancer was hospitalized under the diagnosis of pneumonia. She received a concurrent chemoradiotherapy (CCRT) for esophageal cancer 14 months before. During this hospitalization period, an aortic arch pseudoaneurysm was discovered on the computerized tomography scan. The pathogenesis of pseudoaneurysm may be caused by the weakness of arteriosclerotic vessel walls and structural anomaly. It is rare but often a fatal condition post CCRT. We consulted the specialists and discussed the risks and benefits of surgical intervention with the patient and her family. They decided to receive a thoracic aortic aneurysm (TAA) stent-graft and her symptoms subsided after surgery. We herein report and discuss the clinical diagnosis and management of this rate case.