Objective: To investigate the anatomical characteristics of epicondyle of the humerus and clinical application of refractory tennis elbow with three points-acupotomy-releasing Therapy. Methods: The anatomical and observed eight of 16 cases of adult cadavers specimens elbow epicondyle of the humerus anatomy and morphological characteristics, using knife, "Lysis three" treatment of 48 patients with refractory tennis elbow. Results: The long extensor carpi, carpi brevis, extensor digitorum epicondyle of the humerus important anatomic structure attached, using knife "three Lysis' treatment 48 patients with refractory tennis elbow cure 42 cases, improved in 4 cases, 2 cases, the total efficiency of 95.83%. Conclusion: The knife "three Lysis" treatment of refractory tennis elbow is simple, short course, the advantages of safe, worthy of promotion.