Comparative Analysis of Chlorhexidine Gluconate, Povidone Iodine and Chloroxylenol as Scrubbing Solution

A. S. Yakubu ； A. A. Abubakar ； M. D. Salihu ； A. Jibril ； I. Isah

《British Journal of Pharmacology and Toxicology》 1卷2期 (2010/11) Pp. 93-95

並列摘要

The study was carried out to determine the efficacy of stock concentration of the commonly used disinfectant as scrub solution for surgical site in goats. The evaluation of efficacy and safety of commercially available disinfectant and antiseptic (0.3% Chlorhexidine gluconate, 0.4% Chloroxylenol and 4% Povidone iodine) as scrub solution for surgical site, using stock concentration was assessed in thirty (30) Red Sokoto goats undergoing non elective surgical procedures at Usmanu Danfodiyo University, Veterinary Teaching Hospital and Zonal Veterinary Clinic, Sokoto. Colony counting was used to quantify skin bacteria Colony Forming Unit (CFU) at surgical site before and after skin preparation. Reduction of CFU before and after preparation was significant with all the three disinfectants compared (p＜0.05) and the result shows that Povidone iodine and Chloroxylenol to be less effecacious than Chlorhexidine gluconate when mean colony forming unit after two minute of preparing the surgical sites.

並列關鍵字

Chlorhexidine gluconate ； chloroxylenol ； povidone iodine ； red sokoto goat ； scrubbing solution ； surgical site