- 期刊
Lung Cancer Smaller Than 3 cm With Distant Metastasis: the Relationship of F-18 Fluorodeoxyglucose Metabolism and Anatomic Structure Change
小於3 cm的肺癌併遠處轉移：氟-18去氧葡萄糖代謝與解剖結構改變的關係
摘要
Purpose: To explore the possibility of lung cancer smaller than 3 cm associated with distal metastasis. Methods: We collected patients who have lung cancer smaller than 3 cm with distant metastasis retrospectively, and the patients are uncommon. All the 27 patients whose medical records and results of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) scan after the initial diagnosis as available were included. Among them, 14 patients (group A) were lung cancer tumor sizes larger than 1 cm and smaller than or equal to 2 cm; 13 patients (group B) were tumor sizes larger than 2 cm and smaller than or equal to 3 cm. Results: A total of 27 patients whose lung cancer was smaller than 3 cm with distant metastasis were analyzed. The measurement of lung cancer tumor size was 1.2-2.9 cm, the maximum standardized uptake value was 2.4-23.2, and the visual score was 1-4. All of them have FDG uptake, including 5 and 4 patients in Group A and B respectively associated with pleural contact. Observed patterns of lung cancer CT images vary as follows: 6 (22.2%) patients have a linear pleura tag pattern, 5 (18.5%) patients have a pleura retraction pattern, 16 (59.3%) patients have a pleura thickening and contact pattern. In addition, 5 patients with lung cancer involve the vessel. Conclusion: FDG PET/CT shows lung cancers smaller than 3 cm with FDG uptake, involving the vessel, pleura change, and tumor nearby pleura are the risk of the possibility of distant metastasis.
並列摘要
背景：探討小於3cm肺癌與遠端轉移相關的可能性。方法：我們回顧性收集了小於3cm且有遠處轉移的肺癌患者，這些患者並不常見。納入初步診斷後病歷紀錄和有F-18 fluorodeoxyglucose positron emission tomography/computed tomography（FDGPET/CT）掃描，結果可用的有27例患者。其中，14例（A組）肺癌腫瘤大於1 cm且小於等於2 cm；13例（B組）腫瘤大於2 cm且小於等於3 cm。結果：共分析27例肺癌小於3 cm遠處轉移的患者。肺癌腫瘤大小測量為1.2～2.9 cm，SUVmax為2.4～23.2，視覺評分為1～4分。27例患者皆存在FDG攝取，A組和B組分別有5例和4例伴有胸膜接觸。肺癌CT圖像的觀察模式變化如下：6例（22.2%）患者有線性胸膜標籤模式，5例（18.5%）患者有胸膜回縮模式，16例（59.3%）患者有胸膜增厚和接觸模式。此外，5例肺癌患者侵犯及血管。結論：FDGPET/CT顯示小於3 cm的肺癌伴有FDG攝取，侵犯血管、胸膜改變、腫瘤鄰近胸膜，則有遠處轉移的風險。