High-intensity exercise will induce the production of reactive oxygen species. If a large amount of it accumulates in the body, it will cause oxidative stress, cause cell oxidative damage, break the redox balance, and affect your own health. The human body has its own oxidative damage protection system, that is, when the oxidative balance in the body is broken, it will produce non-enzymatic antioxidants such as vitamin E, vitamin C, carotenoids, etc. to protect the body from oxidative damage. With the emergence of various supplements, reducing the active oxygen and reactive nitrogen (ROS/RNS) produced by exercise through exogenous intake of antioxidants has become a popular antioxidant model. As a powerful antioxidant, astaxanthin has gradually become a hot topic. In addition to its antioxidant capacity, it also has the ability to relieve fatigue, promote recovery, and anti-inflammatory. This article mainly discusses the role of astaxanthin as an antioxidant from the perspective of exercise. The performance mechanism in the body is intended to provide a reference for reducing the oxidative damage of the human body during exercise.