Calcium, Osteoporosis Treatment, the Women's Health and the Future Development of Calmodulin

鈣、骨質疏鬆症治療、婦女健康和鈣調蛋白的未來發展

林琳(Lin Lin) ； Fa-Sain Lo ； Amiya Bhaumik ； Divya Midhun Chakkaravarthy

《休閒運動健康評論》 10卷1期 (2021/03) Pp. 107-117

摘要

Osteoporosis is a common disease especially among the elderly female demographic. Its occurrence can be found in cross-culture, region, and social status. There are several treatments existed with proven result to manage the symptom of osteoporosis, and a new research area on calmodulin is emerging. The underlying cause is calcium deficiency, and it ties closely to women in different stages of their life. At each stage, calcium is used for different functions and without sufficient supply, the continuous expenditure on the body's calcium deposit will eventually result in osteoporosis.

關鍵字

osteoporosis ； calcium deficiency ； women's health ； nutrition supplement ； calmodulin

並列摘要

骨質疏鬆症是一種常見疾病，尤其是在老年女性人群中。它的發生是跨文化、地區和社會發展的。已有多種治療方法能有效地防止骨質疏鬆症，鈣調蛋白正成為一個新的研究領域。根本原因是鈣不足，它與女性的生活不同階段密切相關。在每個階段，鈣都有不同的功能，並且鈣供應不足，加上人體的持續消耗，最終將導致骨質疏鬆症。

並列關鍵字

骨質疏鬆症 ； 鈣缺乏症 ； 婦女健康 ； 營養補充 ； 鈣調蛋白

參考文獻

National Institute of Health (2020). Calcium, fact sheet for health professionals. October 23, 2019 Retrieved from: https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/National

Osteoporosis Foundation (2021). What Women Need to Know. March 31, 2021 Retrieved from: https://www.nof.org/preventing-fractures/general-facts/what-women-need-to-know/#:~:text=Of%20the%20estimated%2010%20million,breast%2C%20uterine%20and%20ovarian%20cancer.

Plotkin, L., Weinstein, R., Parfitt, A., Roberson, P., Manolagas, S., & Bellido, T. (1999). Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin.The Journal of Clinical Investigation, 104, 1363-1374

Seales, E. C., Micoli, K. J., & McDonald, J. M. (2006). Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival. Journal of Cellular Biochemistry, 97, 45-55

Sozen, T., Ozisik, L., & Basearan, N. C. (2017). An overview and management of osteoporosis. European Journal of Rheumatology, 4(1), 46-56