• 期刊

Variability of Surface Morphology in Stratum Corneum Rat Oral Keratinocytes

從老鼠各取下40個頰部及舌腹粕膜，分別以掃描式電子顯微鏡觀察其表面形態。結果委現頰部與舌腹粕膜皆為正角質化上皮，且兩者之表面形態並無差異。角質上皮皆以不規則之鱗狀重疊而成，而上皮細胞則呈多邊形並緊密的排列一起。細胞界線則由單嵴或雙嵴組成。表面形態則呈多樣性－或呈迷宮狀的嵴形摺疊突起，摺疊突起之周圍則包燒著小窪谷，此種形態最常見；其次則為凹陷小坑狀之形態，小坑多呈規則圓形、淺薄凹洞；絨毛般小突起之形態則偶而可見；有時，上述三者合併出現之混合形態亦頗常見。四種多樣性之表面形態未曾有人報告，本實驗之發現可提供日後觀察各種口腔上皮表面形態之參考。

• 期刊

Patient Dose from Panoramic Dental X-Ray Exposures with Different Screen/Film Combinations

本研究目的在測示舊型環口放射攝影機經改用新型的稀土類增感屏(rare-earth screen)作放射線攝影對頭頸部若干部位組織輻射劑量的改變，並評估不同kVp/mA/增感屏/軟片組合對影像對比(radiographic contrast)之影響。測量結果發現使用稀土類增感屏需同時調降kVp與mA值，因而減少病患輻射劑量達20％至60％，亦能維持良好影像對比，値得推廣使用。特提供目前仍使用舊型環口放射攝影機器配備非稀土類增感屏的牙醫師參考。

• 期刊

常見口腔粘膜病灶與正常口腔粘膜之介白質－1β含量之研究

Interleukin-1β(IL-1β)has been proven to be a multi-effect medium of inflammation. It is a polypeptide and is the principal form of interleukin-1.Its source cells total over twenty and its effects cover both immune cells and non-immune cells. In endothelium, it makes it easier for inflammatory cells to move from the blood to the inflamed tissues. In fibroblast, it can regulate the synthesis and decomposition of extra-cellular matrix. It can also indirectly cause bone absorption and inhibit bone growth. It is therefore evident that IL-1β plays a variety of roles, however, most current research is aimed at investigating the content of IL-1β in body fluids and single cell culture solution. Research into the total amount of IL-1β in tissue blocks in more seldom encountered, and there is a particular dearth of research into the total amounts of IL-1β present in oral lesions. Therefore, this study used the method of enzyme linked immunosorbent assay (ELISA) to perform a statistical comparison between the amounts of IL-1βpresent in normal oral mucosa and that present in oral submucous fibrosis (OSF), squamous cell carcinoma (SCC), and verrucous hyperplasia (VerH). The results found that the amounts of IL-1β present in normal oral mucosa, OSF, SCC, and VerH respecitively are 1.071±0.53 pg/mg tissue (mean±SD), 0.76±0.56 pg/mg tissue, 4.37±0.87 pg/mg tissue, and 3.97±1.93 pg/mg tissue. Listed in descending order, these are SCC VerH, normal, and OSF. Performing a Mann-Whitney U Test shows that there is no significant difference (p＞0.05) between the amount of IL-1β present in normal oral mucosa and oral submucous fibrosis, however there was a significant difference (p＜0.001) between the amount of IL-1βpresent in normal oral mucosa and both squamous cell carcinoma and verrucous hyperplasia. There exists no significant difference between the amount of IL-1β present in SCC and VerH. It can be seen from the above results that the amounts of IL-1β present in SCC and VerH are obviously higher than that of normal oral mucosa and OSF. This shows that there is a correlation between the amount of IL-1β in tissue blocks and both the degree of inflammation and cell transformation. On the other hand, the fact that there is no significant difference between the amounts of IL-1β present in normal oral mucosa and OSF shows that the amount IL-1β does not change significantly as the disease progresses. Analysis also shows that the amount of IL-1β present in oral submucous fibrosis tissue blocks in unrelated to the seriousness of the disease. Thus, IL-1β levels cannot be used to gauge the seriousness of fibrosis.

• 期刊

臺中榮民總醫院1987-1991年顏面部骨折調查

統計台中榮民總醫院1987-1991年五年中，因顏面骨折住院病患共245人。患者的年齡層主要21-30歲(32％)及11-20歲(26％)。平均年齡31歲，男女比爲2.7:1。骨折原因以交通意外85.4％最多，而以機車事故74.4％最高。顏面中部骨折以颧骨骨折最多，而下頜骨骨折以中央部骨折最多。國内因交通意外造成顏面骨折所佔比例較國外高出數倍。

• 期刊

Mandibular Punched Out Lesions of Myeloma-Report of a Case

一位敬老院女性年老病患來院主訴背痛、胸痛。右側下顎骨處亦有輕微壓痛。骨髓檢查發現多量之惡性漿細胞。免疫電泳檢查爲IgG-K單株蛋白。確立診斷爲多發性骨髓瘤病例。下顎骨之放射線檢查及環口X光攝影顯示有骨質溶解性病灶。顱骨亦有同樣發現。病患經化學治療後顯示下顎骨病灶稍有改善進步。台灣目前骨髓瘤併顱骨侵犯之發生率尚未有正式統計。顎骨骨髓瘤轉移之報告亦未見諸國内文獻。此例報告顯示下顎骨侵犯應爲骨髓瘤之晚期表現，而非原發徵候。

• 期刊

應用冠狀切開術治療顏面部多處骨折－三病例報告

現今治療顱顏面部骨折的潮流，主要依循下列五項準則：(1)正確的診斷。(2)直接展現所有骨折區。(3)精確將骨片復位至原解剖位置並加以固定。(4)立即式地骨頭移植。(5)將骨膜及軟組織作確定性縫合修補。依循上述幾項原則，以往傳統延遲處理骨折所造成的軟組織疤痕攣縮及骨頭未正確復位導致的顏面變形等情況，將因此大爲降低。爲了將所有骨折斷片呈現於術者面前，達到精確復位及固定的目的，適當的選擇手術切線益形重要。冠狀切開術提供術者中上顏面部良好的手術視野，配合其他切線，更能將顏面骨折區域一覽無遺。本文報告三複雜性顏面骨骨折病例，應用冠狀切開術展示骨折區，獲致令人滿意的結果。

• 期刊

口腔底部皮樣囊腫－病例報告

皮樣囊腫在全身是一種常見的疾病，但發生在口腔底部卻十分少見。長庚醫院病理科從1988年至1995年共診斷555例皮樣囊腫，其中僅有四例發生在口腔底部，發生率0.7％。本篇報告爲至口腔外科求診的兩個病例。一爲12歲女孩，在右側舌下區長一4.5×3.5×3.5公分的皮樣囊腫。經由口内手術摘除。另一為20歲女性，在口底正中、兩側頦舌肌及頦舌骨肌之間，有一5.5×5×5公分的皮樣囊腫。經由口内及口外合併手術摘除。本篇同時回顧有關的文獻，並藉以探討皮樣囊腫的病因、發生率、分類、臨床特性、鑑別診斷及治療方法等。