輔仁醫學期刊/Fu-Jen Journal of Medicine
輔仁大學醫學院,正常發行
選擇卷期
- 期刊
Background and purpose: Overactive bladder (OAB) is a syndrome characterized by urgency and frequency, with or without urge incontinence. Extracorporeal electromagnetic stimulation (EMS) has been successfully applied for the treatment of stress and urinary urge incontinence. We report our experience of using extracorporeal electromagnetic stimulation for patients with OAB and urinary incontinence, and investigate predictors for successful treatment. Methods: Between 2009 and 2016, 162 patients (88 women and 74 men), who presented with OAB symptoms and urinary incontinence treated with EMS treatment, were enrolled in this study. Treatment results were assessed by global response assessment. The overactive bladder symptom score (OAB-SS) questionnaire was recorded before and after treatment. Logistic regression analysis was used to identify predictors for an improved outcome. Results: All patients tolerated the treatment without any adverse event and mean age was 66.9 ± 13.8 years. In total, 103 patients (63.6%) reported improved outcomes (GRA ≧ 1). The mean total OABSS score decreased significantly after treatment (10.4 ± 3.1 versus 6.1 ± 3.5, p ＜ 0.01). Pure stress urinary incontinence patients showed less improvement when compared to patients with mixed urinary incontinence or pure urgency urinary incontinence. Male patients without a previous history of transurethral resection of prostate history (odds ratio = 3.17, p=0.03) could serve as predictors of a satisfactory outcome. Conclusions: Treatment course involving EMS of the pelvic floor can improve the symptoms of most OAB patients with synchronous incontinence symptoms. EMS could therefore be considered as an alternative treatment for patients with OAB.
- 期刊
Skin aging includes intrinsic and extrinsic aging. The factors enhancing the extrinsic aging is sunlight exposure and environmental pollution. Previous studies have shown that both sunlight exposure and environment pollution increase the production of reactive oxygen species (ROS), such as singlet molecular oxygen, superoxide radical anion or peroxyl radicals. These lead to photooxidative stress. Photooxidative stress is induced by UV-irradiation via light-dependent formation of reactive oxygen species. Chemical reactions of these reactive intermediates with cellular lipids, proteins and DNA are thought to play a role in the pathobiochemistry of disease affecting light-exposed tissues such as the skin. In skin, the defense system including the enzymatic or nonenzymatic substances can overcome against the ROS. However, if the ROS is overproduced in skin, it causes skin aging, cancer, or wrinkle. The compounds of Ganoderma tsugae, tsugaric acid, show a variety of biomedical efficacies such as antiaging and antioxidation. Therefore, the goal of this study is to evaluate the protective effects of tsugaric acid on skin photoaging. Furthermore, the mechanism on anti-photo injury of tsugaric acid was investigated. From this study, an ideal compound extracted from Ganoderma tsugae, tsugaric acid, was discovered, which might be developed for skin care as an anti-photoaging agent in the future.
- 期刊
Emphysematous cystitis is a rare bacterial infection of urinary bladder wall and is characterized by the presence of gas in the bladder wall, lumen, and surrounding tissues. Diabetes mellitus, dysuria, and neurogenic bladder with voiding dysfunction are the most important risk factors associated with this infection, which predominantly occurs in females. Here we present a case of emphysematous cystitis in a 54-year-old female with diabetes mellitus. Her symptoms improved following treatment with intravenous antibiotics, drainage of urinary bladder, and control of blood sugar level; she was discharged 15 days after admission.
- 期刊
The wound management of skin graft donor site needs a desirable dressing material which can promote healing, cause minimal pain and scarring, prevent infection, inexpensive, and easy to use. In this regard, we reported the calcium alginate dressing which was effectively used on the split thickness of skin graft donor site for three burn patients. The burn patients who have grafting thickness donor site wound are dressed with calcium alginate dressing. The symptoms of pain were assessed by Word Descriptor Scale and Vancouver Scar Scale which indicated hypertrophic scar of the patients. The patients were observed for a period of post-operative from 1 day to 6 months, which showed the efficacy of calcium alginate dressing to give full healing of split skin graft donor sites. Moreover, calcium alginate dressing over donor site were convenient, easy removable, and almost painless for preferred dressing intervention.
- 期刊
Prostate cancer is one of the most common malignancies in men. It often metastasizes to the regional lymph nodes, but neck lymph node involvement at the initial clinical presentation is rare. In this paper, we report a 74-year-old man who initially presented with an enlarged supraclavicular lymph node due to metastatic prostate cancer, which was confirmed by immunohistochemistry.
- 期刊
Tetanus is a rare but lethal disease in developed countries. We report a case involving a 68-year-old man who presented to our hospital with trismus, opithotonus with neck pain, and episodic apnea. He had an open wound in his right index finger that had not received appropriate treatment. Tetanus immunoglobulin G was administered. Endotracheal intubation and subsequent tracheotomy with a ventilator were performed with total sedation with midazolam and diazepam. To relieve the persistent muscle spasm, magnesium sulfate and baclofen were added. He completely recovered after 40 days of hospitalization. Although tetanus-related mortality is rare in Taiwan, prompt diagnosis and empirical treatment are necessary.