- 期刊
外因性內分泌干擾物對魚類生殖的影響
Effects of Exogenous Endocrine Disruptors on Fish Reproduction
摘要
廣布在環境中的外因性內分泌干擾物是近來生態、環保領域關注的焦點。本文將先從「魚類生殖」的觀點，討論外因性內分泌干擾物作用的可能機制。再以「壓力－暴露－影響模式」來分析外因性內分泌干擾物從存在於環境中，輾轉進入魚體內，及對魚體造成影響的三個階段。最後，應用「層級理論」的概念來整合關於魚類生殖的各種生態層次影響。透過這三種觀點所構成的暫時性架構，經由對相關研究的重新整理，發現目前在不同環境下的魚類，其暴露到外因性內分泌干擾物之現象是全面且顯著的。在生殖影響的面向，雖有許多異常、負面的訊息出現。然而，現今對於作用機制上解釋的掌握、壓力與影響關連性的解釋、及生態可能影響皆仍嫌不足，尚待突破。未來相關研究應更細緻地探究生殖內分泌系統在掌握生殖過程的作用機制；再者，透過統整生物性及化學性兩大類指標來建立壓力與影響間的關連性及進一步評估對生態可能影響。
並列摘要
Widespread exogenous endocrine disruptors in the environment are becoming a major growing concern in the field of ecology and environmental protection recently. The objective of this review article is to elucidate the effects of fish reproduction caused by exogenous endocrine disruptors. First, fish reproductive biology will be discussed at different reproductive stages to help understand the possible mechanisms which exogenous endocrine disruptors alter fish reproduction. Second, by incorporating the concept of ”Stress-Exposure-Effect model”, possible effects of exogenous endocrine disruptors can be analyzed in the following three steps: the status of exogenous endocrine disruptors in surroundings, the processes of these chemicals entering the body of fish, and the effects on fish reproduction. Finally, we apply the ”Hierarchy theory” approach to organize all effects causing by exogenous endocrine disruptors from different biological organization levels on fish reproduction. Furthermore, we propose a tentative framework by combining with these three perspectives based on published studies on this subject. From available data, it indicates that fish exposed to exogenous endocrine disruptors worldwide. However, we are still not able to predict the potential ecological outcomes from the disruption of fish reproduction causing by these chemicals. In summary, it will be helpful to make a better prediction on ecological effects of exogenous endocrine disruptors by developing a suite of appropriate biological responses across different biological organization levels by applying an integration of both chemical and biological indicators approaches.